Immuron recruiting patients for ASH trial
Immuron (ASX:IMC) has commenced recruitment for a phase II trial of IMM-124E in alcoholic steatohepatitis (ASH) and arranged to license the treatment candidate in alcohol-induced liver toxicity.
The company has enrolled the first three of a planned 66 patients for a US National Institutes of Health (NIH) sponsored trial in ASH.
The NIH has selected IMM-124E as one of three candidates for its ASH trials. ASH, which is a syndrome of progressive inflammatory liver injury associated with heavy drinking, has a poor prognosis and no currently approved drugs to treat it.
IMM-124E is designed to treat fatty liver associated with ASH and non-alcoholic steatohepatitis (NASH). It is produced using bovine colostrum powder harvested from dairy cows immunised with an Immuron vaccine.
Immuron is separately selecting patients for a NASH trial, and plans to commence recruitment shortly.
Immuron meanwhile revealed it has signed a deal with Immune Biologics covering the licensing of IMM-124E for the treatment of short-term alcohol-induced liver toxicity.
As part of the agreement, Immune Biologics will conduct clinical trials testing the efficacy of IMM-124E in the condition. If the trials prove successful, Immuron will grant Immune Biologics a worldwide licence covering IMM-124E to treat alcohol-induced liver toxicity.
“Immuron’s clinical focus with IMM-124E is the development of prescription products for chronic liver diseases such as NASH and ASH,” CEO Amos Meltzer commented.
“The opportunity to license out the use of IMM-124E for a new indication, with the prospect of early revenues, is another illumination of the versatility of Immuron’s platform technology.”
Immuron (ASX:IMC) shares were trading 2.63% lower at $0.185 as of around 1 pm on Monday.
Personality influences the expression of our genes
An international research team has used artificial intelligence to show that our personalities...
Pig hearts kept alive outside the body for 24 hours
A major hurdle for human heart transplantation is the limited storage time of the donor heart...
Breakthrough antibiotic for mycobacterial infections
The antibiotic candidate, named COE-PNH2, has been optimised to target Mycobacterium...